Knowledge Resources

Beta Carotene Microspheres – Laboratory Trial

Derived from the word ‘Beta’ and ‘Carrot’, ‘Beta Carotene’, is a plant pigment found in carrots. Beta Carotene while entering our body gets converted into Vitamin A which is an essential micronutrient. It helps one maintain good vision, lining of respiratory tract, regulation of skin cells and proteins. All carotenoids, including beta-carotene, also possess antioxidant […]

Process

Pharmaceutical Product Development – in Perspective and Practice

The following discussion is primarily in the context of development of expired Generic or Patent pharmaceutical dosage forms, which can be pharmaceutically and bio pharmaceutically equivalent to an established international brand leader (Innovator). However, it is neither intended nor should it be perceived as a New Molecule (New Drug Product) Development. While considering a new […]

Process

High Shear Granulations (HSG) Vs Fluid Bed Granulations (FBG) – A differentiation guide

Granulation that forms the core component of the pharmaceutical industry continues to grow with improved technologies and accelerated advancement.  Apparently, High Shear Granulation (HSG) technique that offers an enhanced shaping process has been widely accepted as the optimum choice of tablet granulation method. Considering its slow moving heavy duty beater assembly coupled with a fast […]

Process

Properties of a Good tablet granulation

What are the ideal properties of a good tablet granulation? Again a very loaded question but a very frequently asked question too. Let us try to identify the ideal properties and try to give them some usable numbers and figures. The properties of a good granulation can be defined as below: Flowability  Optimum Moisture content Good […]

Process