Process

Prefilled Syringe – The Smart Spike

As I write this blog, it is quite likely that a transformation is taking place somewhere. This change could be small or, at other times, so big that it can lead to a huge impact all around. And the past few years have been a testimony to evolution across a wide array of industries. I […]

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GAINFUL GRANULATION vs CORRECT COMPRESSION – understanding the easy way 

The role of granulation in tablet manufacturing is indisputable. The formation of granules, if characterized optimally, enhances the uniformity of the API, and has significant impact on the tablet’s flowability and compressibility. As we all know, several manufacturing unit operations are undertaken prior to tablet compressing, including wet granulation to agglomerate ‘fines’ and form appropriate […]

Process

Beta Carotene Microspheres – Laboratory Trial

Derived from the word ‘Beta’ and ‘Carrot’, ‘Beta Carotene’, is a plant pigment found in carrots. Beta Carotene while entering our body gets converted into Vitamin A which is an essential micronutrient. It helps one maintain good vision, lining of respiratory tract, regulation of skin cells and proteins. All carotenoids, including beta-carotene, also possess antioxidant […]

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Pharmaceutical Product Development – in Perspective and Practice

The following discussion is primarily in the context of development of expired Generic or Patent pharmaceutical dosage forms, which can be pharmaceutically and bio pharmaceutically equivalent to an established international brand leader (Innovator). However, it is neither intended nor should it be perceived as a New Molecule (New Drug Product) Development. While considering a new […]

Process

High Shear Granulations (HSG) Vs Fluid Bed Granulations (FBG) – A differentiation guide

Granulation that forms the core component of the pharmaceutical industry continues to grow with improved technologies and accelerated advancement.  Apparently, High Shear Granulation (HSG) technique that offers an enhanced shaping process has been widely accepted as the optimum choice of tablet granulation method. Considering its slow moving heavy duty beater assembly coupled with a fast […]

Process

Properties of a Good tablet granulation

What are the ideal properties of a good tablet granulation? Again a very loaded question but a very frequently asked question too. Let us try to identify the ideal properties and try to give them some usable numbers and figures. The properties of a good granulation can be defined as below: Flowability  Optimum Moisture content Good […]

Process

The trial at Application Service Centre Part-II

This blog is a continuation of the Tech trial series Part-I where we talked about the development of NPS sugar beads from sugar powder using Fluid Bed Columns for one of our customers. In this series, we take our trial one step ahead for developing the sugar beads by using a dry powder layering technique […]

Process
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